Dr. Bondurat,
I rewrite the synthesis because I thought that the other one was't clear,This file includes synthesis, reterosynthesis, and the website that I've used.
Padideh.R
Padideh: This is a good synthesis, I see no problems with it. My only suggestion is to provide a reterosynthesis, a word description, and page numbers where these reactions may be found. Bruce Bondurat
Dr. Bondurant,
Here is my synthesis for Tremorine. You will find a brief description of the synthesis below the photo. Thanks for your review and any insight you may have.
Sean Croteau
First the sodium amine is added and sodium carbene is formed. Next, the sodium carbene is synthesized with methyl iodide. This will eliminate the presence of Na and turn it into NaI. The sodium amine then is analyzed with methyl iodide, and in the presence of NBS at equilibrium, 1,2- bromo alkyne is formed. Lastly, adding 2N2HCO3, C4H3Br2 and toluene will present you with the final product --- Tremorine.
Place syntheses below
Dr. Bondurat,
I rewrite the synthesis because I thought that the other one was't clear,This file includes synthesis, reterosynthesis, and the website that I've used.
Padideh.R
Padideh:
This is a good synthesis, I see no problems with it. My only suggestion is to provide a reterosynthesis, a word description, and page numbers where these reactions may be found.
Bruce Bondurat
Dr. Bondurant,
Here is my synthesis for Tremorine. You will find a brief description of the synthesis below the photo. Thanks for your review and any insight you may have.
Sean Croteau
First the sodium amine is added and sodium carbene is formed. Next, the sodium carbene is synthesized with methyl iodide. This will eliminate the presence of Na and turn it into NaI. The sodium amine then is analyzed with methyl iodide, and in the presence of NBS at equilibrium, 1,2- bromo alkyne is formed. Lastly, adding 2N2HCO3, C4H3Br2 and toluene will present you with the final product --- Tremorine.
L.G. Wade Jr. Organic Chemistry 7th edition.
http://www.organic-chemistry.org/abstracts
Sean Croteau
Sean:
This is good Simply upload a reterosynthesis and you have it.
Bruce Bondurant
This looks good.
(EXTRA CREDIT SYNTHESIS)
=TREMORINE RETROSYNTHESIS:=
TREMORINE SYNTHESIS:
HOW TO SYNTHESIZE TREMORINE: